The effectiveness of lifestyle interventions in reducing cardiovascular risk and risk factors in people with prediabetes: A systematic review and meta-analysis

Abstract

Aim: This systematic review and meta-analysis examined the effectiveness of lifestyle interventions in reducing cardiovascular disease (CVD) risk, CVD events, and related risk factors among individuals with prediabetes. Data synthesis: We conducted a search of the MEDLINE, Embase, PsycINFO, CENTRAL, and Scopus databases, along with ClinicalTrials.gov, for lifestyle-based randomized controlled trials (RCTs) involving individuals with prediabetes. Our focus was on interventions that lasted at least six months and were published between 1997 and April 2024. Two authors independently screened the abstracts and titles of the retrieved articles, followed by full-text reviews and data extraction fr..